Cause of vitligo or Leucoderma is not clear. It could be due to accidental cause such as a cut, burn etc. The reason being melanocytes cells (which produce melanin pigment) gets dormant or inactive. Due to this dormancy or inactivity the pigmentation gradually disappears from the skin layers and the skin converts white there resulting into a white patch. Genetic condition which is almost 10-15%, is also attached as the cause of Vitiligo. But this is not certain that all the kids of vitiligo affected parents develop Vitiligo. Several families can be found unaffected despite family history of Vitiligo. In siddha it is tridosha imbalance ie vatha,pitha,kapha imbalance. In ancient text there are many reference and effective medicines in siddha system and also cure for this. In our experience we prepare medicines for complete cure. We give medicines which corrects the tridosha imbalance and also helps in increase of melanocytes. Also externa medicines are applied to those areas so that pigmention increases rapidly. Basic thing is patient should have patience since it takes longer time to correct. The duration of treatment depends upon the area of the affected skin. If vitligo starts from lips,palms,soles or genitalias prognosis is not good. Stress and strain may increase the spread of this disease so we advice the patient yoga or meditation to speed the recovery.